Healthcare Professionals

What makes STAVZOR unique

STAVZOR (valproic acid) is a patented, delayed-release soft gel capsule formulation of valproate for the treatment of the manic episodes associated with bipolar disorder, as well as epilepsy and migraine headache prophylaxis.

STAVZOR small, easy-to-swallow soft gel capsules are an innovative valproate formulation formulated to help your patients start — and stay on — their therapy.

Here's what makes STAVZOR unique:

Small, soft gel capsules are easy to swallow with enteric technology formulated to reduce reflux and gastric irritability
Patients save money on every STAVZOR prescription

Other features of STAVZOR:

Patients prefer clear oval soft gel capsules
It's easy for your patients to find

STAVZOR soft gel capsules are easy to swallow

STAVZOR small size, soft gel formulation makes capsules easy to swallow.

STAVZOR soft gel capsules in the 500mg dosage form are up to 40% smaller than Depakote® or Depakote ER&®* (divalproex sodium) tablets. These features make the capsules easy for patients to swallow – and obviate the need for sprinkling the contents of a capsule on food.

Enteric technology formulated to reduce reflux and gastric irritability

STAVZOR soft gel capsule is formulated for favorable GI tolerability. Enteric properties in the clear, soft gel allow the valproate to be absorbed in the small intestine rather than in the stomach, where standard formulations of valproic acid are absorbed. This may reduce the potential for reflux and gastric irritability.

The capsule shell is resistant to gastric acid, but when exposed to intestinal pH, it ruptures and releases the valproic acid. In addition, time to maximum plasma concentration occurred at 2.3 hours compared with 3.7 hours with divalproex delayed-release tablet — indicating faster absorption with overall extent of absorption being comparable and demonstrated bioequivalence.

[ STAVZOR is absorbed in the small intestine, not the stomach. ]
Absorbed in the small intestine, not the stomach.

Patients prefer clear oval soft gel capsules

When asked to view various dosage forms, 71% (86% female) of consumers preferred clear oval soft gels. And a new patient survey confirms that 83% of Depakote/Depakote ER* patients would prefer soft gel capsules like STAVZOR as long as it was equal in effectiveness and side effects, chart data on file

More about patient pill preferences

It's easy for your patients to obtain

Noven Therapeutics is making it easy for your patients to fill their prescription.

Remind your patients there is no generic form of STAVZOR. They should receive a small, orange soft gel capsule.

*Depakote/Depakote ER (divalproex sodium) are registered trademarks of Abbott Laboratories, North Chicago, IL.