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Stavzor

Help prevent common triggers

Feeling stressed, missing sleep, skipping your bipolar disorder medication — these are some of the common triggers that can prompt a bipolar mood episode. They also can be a warning sign of an existing episode.

That's why it's important to recognize your common triggers and stressors – the external factors that can change your moods. When you are aware of disruptions in your "Social rhythm" or the other events most likely to trigger bipolar mood swings, you can work with your doctor and family to plan strategies to help you stay well.

A bipolar disorder wellness plan includes:

  • Medication
  • Regular doctor visits
  • Psychotherapy
  • Understanding your triggers – recognizing, avoiding and responding to them

Here are common triggers of bipolar episodes — and how you can help manage them.

Stress

Few people live stress-free lives these days, and having a serious illness like bipolar disorder can add to the pressures. Individuals with bipolar disorder are at additional risk for episodes since certain life events can precipitate mood swings. Stressors include:

  • Social rhythm disruption such as going on vacation, staying up late, moving to a new city
  • Negative life events including divorce, job loss, death of a family member
  • Other less severe life events such as a fight with a family member or other family conflict
  • Positive life events such as starting a new job or graduating from school

Your wellness plan. Make a list of the major stressors in your life and work together with your doctor to create a wellness plan to manage the stressors. Physical activity, meditation, guided imagery (positive thinking) and spirituality — these are just some of the methods that can be used to calm yourself. Find the ones that work best for you. Also, keep to a regular schedule, including the times you go to bed and eat meals.

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Did you know that 65% of bipolar patients with manic episodes experienced at least one social rhythms disruption event shortly before an episode?

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Irregular sleep schedule

Sleeping too much or too little are typical symptoms of bipolar disorder. Not enough sleep can actually precipitate a manic episode as well. Even a single night of lessened sleep can create the problem.

Your wellness plan. Arrange your schedule so you don't need to stay up late studying or working on a project for your job. Also pay attention to your late night socializing, Internet surfing or video watching. Develop a sleep schedule that includes going to bed and rising at approximately the same times each day. If stressors are keeping you from getting sufficient sleep, ask your doctor for advice. Insomnia is both a trigger and a symptom of a manic episode.

Effects of Sunlight

Bipolar disorder symptoms can increase with a rapid rise in bright sunshine. Bright light can affect the pineal gland and trigger depression and mania. The pineal gland produces the hormone melatonin, which may modulate wake/sleep patterns (called the circadian rhythm.)

Your wellness plan. Talk to your doctor if increased sunlight during springtime and early summer seems to be a mood trigger for you.

Alcohol or drug abuse

Substance abuse and bipolar disorder often coexist. People with bipolar disorder may use alcohol during manic episodes to "self medicate" — extending their euphoric state or dampening their agitation. Substance abuse, however, greatly worsens bipolar disorder. Individuals with bipolar disorder who abuse alcohol or drugs are also more likely to skip their medications.

Your wellness plan. If you are abusing alcohol or other drugs, talk to your doctor about the best ways to treat the addiction. You also may want to consider a self-help group such as Alcoholics Anonymous.

Not taking your medications

When you are feeling well, you may not believe it's necessary to continue taking your medications. But skipping your therapy, which is called "noncompliance," makes a mood relapse more likely.

Medications are the cornerstone of treatment in bipolar disorder. Staying on treatment, even during the times you feel well, can help you keep your disease under control and reduce the chance of worsening, recurrent episodes.

Your wellness plan. Take your medication as your doctor prescribes. If you are experiencing side effects that are making you skip doses, contact your doctor for advice. Your doctor will work with you to adjust your therapy to relieve side effects.

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Did you know there is a mood stabilizing medication that comes in a small, easy-to-swallow soft gel capsule that patients prefer? STAVZOR is valproic acid medication that's up to 40% smaller than other valproate medications (in 500 mg dosage formulation).

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Illnesses that may co-exist with bipolar disorder

People with bipolar disorder often have abnormal thyroid function. Too much or too little thyroid hormone could be a risk factor for mood changes.

  • Your wellness plan. Your thyroid levels should always be monitored by your doctor. If appropriate, you may be prescribed a thyroid supplement.

Managing your triggers

Recognizing and managing your triggers — plus working with your doctor — can help prevent mood swings and help you lead a full, productive life.

Bipolar Symptoms Checker

Important Safety Information You Should Know about STAVZOR

Liver problems Your doctor should check your liver function before you start taking STAVZOR and at frequent intervals while you're on therapy. If you feel generally ill (malaise), weak, and tired, if your face is swollen and you lose your appetite, and start vomiting, call your doctor immediately.

Pregnancy: Birth defectsWomen who can become pregnant need to know that valproic acid has been associated with birth defects, in particular with spina bifida, a condition in which the baby's spinal canal fails to close. If you are planning to become pregnant, you should discuss the risks of birth defects, along with other possible treatment options, with your doctor. If you do become pregnant while taking STAVZOR, call your doctor immediately.
Read more important safety information about pregnancy.

PancreatitisSome people taking valproate have experienced a serious, life-threatening illness called pancreatitis (inflamed pancreas). If you experience stomach pain, nausea, vomiting, and/or loss of appetite, call your doctor immediately.

Common side effects reported in studies with valproate were nausea, drowsiness, vomiting, and dizziness. These are not all the side effects that may occur. You will find a complete list of side effects in the full Prescribing Information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.


Recent Information about Antiepileptic Medications including STAVZOR® (valproic acid) Delayed Release Capsules for any use

For Patients and Caregivers

All antiepileptic medicines, used for any condition, may increase suicidal thoughts or actions in some patients. Pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. Keep all follow-up visits with the healthcare provider as scheduled. Call the healthcare provider between visits as needed, especially if you have concerns about symptoms.

Watch for and call the healthcare provider right away to report if you or your family member see the appearance or worsening of symptoms of depression, any unusual changes in mood or behavior, or the appearance of suicidal thoughts, behavior, or thoughts about self-harm. Behaviors of concern should be reported immediately to the healthcare provider.

For Healthcare Professionals

All antiepileptic drugs (AEDs), including STAVZOR, increase the risk of suicidal thoughts or behavior in patients taking these drugs for any indication. Anyone considering prescribing Stavzor or any other AED must balance their risk of suicidal thoughts and behavior with the risk of untreated illness.

Patients, their caregivers, and families should be informed that AEDs increase the risk of suicidal thoughts and behavior and should be advised of the need to be alert for the emergence or worsening of the signs and symptoms of depression, any unusual changes in mood or behavior, or the emergence of suicidal thoughts, behavior or thoughts about self-harm. Behaviors of concern should be reported immediately to healthcare providers.

For medical inquiries specific to Stavzor, please call 1-800-455-8070