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Stavzor

Bipolar Glossary

Bipolar disorder is a "mood disorder" characterized by periods of mania (excitability) that alternate with periods of depression.

Cyclothymic disorder is a milder form of bipolar disorder that includes hypomania and dysthymia, a milder, chronic form of depression. Full blown manic episodes don't occur.

Depression is characterized by symptoms including a loss of energy, feelings of hopelessness and worthlessness, sadness and loss of interest in things that usually bring pleasure. Individuals may think often about death or committing suicide.

Distortions are a mental process that "distorts" interpersonal communication and perceptions. Distortion typically includes rationalization and denial. Psychotherapy seeks to alter negative perceptions.

Endorphins are one of the body's own painkillers –– chemicals the body produces to suppress pain. Physical activity can release endorphins.

Enteric coatings on a medication are designed to pass unchanged through the stomach and disintegrate in the small intestine.

Episodes are a period of illness, which in bipolar disorder can be manic, depressive or a mixed state.

First–line therapy is the first course of treatment used against a disease or condition. Valproic acid, the active ingredient found in STAVZOR, is a first–line therapy recommended by the American Psychiatric Association to treat the manic episodes of bipolar disorder.

Hypomania is a less extreme state of mania, characterized by a high mood, excitability and overactivity.

Mania is a mood state characterized by unusually "high" or hyperactive mental and physical activity. When these symptoms are present, it's called a manic episode.

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Mood stabilizers are medications that help reduce mood swings and prevent new ones from occurring.

Neurotransmitters are chemicals that act as messengers to the brain's nerve cells.

Psychotherapy, also called "talk therapy" or just "therapy, is a general term for a variety of treatments provided by trained mental health counselors to treat mental illnesses.

Reflux is a flowing back (regurgitation) of stomach acid into the esophagus (the tube carrying food and liquids to the stomach).

Social rhythms are an individual's regular daily activities and interpersonal relationships. Maintaining a regular schedule of daily activities and stability in personal relationships can be beneficial to those with bipolar disorder.

Sleep apnea is a sleep disorder characterized by pauses in breathing during sleep. This may occur many times a night.

Sturge–Weber syndrome is characterized by a port wine birthmark on one side of the face, seizures and sometimes affects the eyes.

Triggers are an event or situation that causes symptoms or an episode in individuals with certain diseases such as bipolar disorder.

Valproic acid is medication used to treat bipolar manic episodes and epileptic seizures. It is also used to help prevent migraine headaches. STAVZOR is a valproic acid medication.

Valproate. This is the active form of valproic acid after it has changed in the digestive tract.

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BIPOLAR SYMPTOMS CHECKER

Learn if you or someone you know may have the symptoms of bipolar mania.


Important Safety Information You Should Know about STAVZOR

Liver problems Your doctor should check your liver function before you start taking STAVZOR and at frequent intervals while you're on therapy. If you feel generally ill (malaise), weak, and tired, if your face is swollen and you lose your appetite, and start vomiting, call your doctor immediately.

Pregnancy: Birth defectsWomen who can become pregnant need to know that valproic acid has been associated with birth defects, in particular with spina bifida, a condition in which the baby's spinal canal fails to close. If you are planning to become pregnant, you should discuss the risks of birth defects, along with other possible treatment options, with your doctor. If you do become pregnant while taking STAVZOR, call your doctor immediately.
Read more important safety information about pregnancy.

PancreatitisSome people taking valproate have experienced a serious, life-threatening illness called pancreatitis (inflamed pancreas). If you experience stomach pain, nausea, vomiting, and/or loss of appetite, call your doctor immediately.

Common side effects reported in studies with valproate were nausea, drowsiness, vomiting, and dizziness. These are not all the side effects that may occur. You will find a complete list of side effects in the full Prescribing Information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.


Recent Information about Antiepileptic Medications including STAVZOR® (valproic acid) Delayed Release Capsules for any use

For Patients and Caregivers

All antiepileptic medicines, used for any condition, may increase suicidal thoughts or actions in some patients. Pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. Keep all follow-up visits with the healthcare provider as scheduled. Call the healthcare provider between visits as needed, especially if you have concerns about symptoms.

Watch for and call the healthcare provider right away to report if you or your family member see the appearance or worsening of symptoms of depression, any unusual changes in mood or behavior, or the appearance of suicidal thoughts, behavior, or thoughts about self-harm. Behaviors of concern should be reported immediately to the healthcare provider.

For Healthcare Professionals

All antiepileptic drugs (AEDs), including STAVZOR, increase the risk of suicidal thoughts or behavior in patients taking these drugs for any indication. Anyone considering prescribing Stavzor or any other AED must balance their risk of suicidal thoughts and behavior with the risk of untreated illness.

Patients, their caregivers, and families should be informed that AEDs increase the risk of suicidal thoughts and behavior and should be advised of the need to be alert for the emergence or worsening of the signs and symptoms of depression, any unusual changes in mood or behavior, or the emergence of suicidal thoughts, behavior or thoughts about self-harm. Behaviors of concern should be reported immediately to healthcare providers.

For medical inquiries specific to Stavzor, please call 1-800-455-8070